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This activates protein kinase A, which then activates hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids that can be burned for energy

For example, it could provide alternatives to surgical interventions in epilepsy, modulate dysregulated pain networks in chronic pain conditions, and offer therapeutic benefits for neurodegenerative diseases such as Alzheimers

However, it remains difficult to modulate the function of factors other than enzymes or signal-dependent nuclear factors by disrupting DNA/protein or protein/protein interactions [41] and such modulation is particularly problematic for factors with important non-erythroid functions [42]